“Caravaggio trained as a painter in Milan before moving to Rome when he was in his twenties. He developed a considerable name as an artist and as a violent, touchy and provocative man. He killed Ranuccio Tommasoni in a brawl, which led to a death sentence for murder and forced him to flee to Naples. There he again established himself as one of the most prominent Italian painters of his generation. He travelled to Malta and on to Sicily in 1607 and pursued a papal pardon for his sentence. In 1609, he returned to Naples, where he was involved in a violent clash; his face was disfigured, and rumours of his death circulated. Questions about his mental state arose from his erratic and bizarre behavior. He died in 1610 under uncertain circumstances while on his way from Naples to Rome. Reports stated that he died of a fever, but suggestions have been made that he was murdered or that he died of lead poisoning”
It never ceases to amaze me what a crazy violent guy he was and yet the church continued to give him assignments, he was just that skilled. Certainly some of his violent instincts are on show in “Medusa”.
There was a lot of trade between Venice and the wealthy Arab world at that point, wouldn’t be surprised if exciting substances came over in the ships, along with spices. Possibly opium, although that was a much bigger deal when the British empire extended to Afghanistan and Hong Kong.